Knowledge Item: CA-Medical Outcomes-01
Patient Health Indicators Near Enrollment by Client Need and Vulnerability Categories

This Knowledge Item shows the levels of three medical indicators of the stage of HIV disease–viral loads, CD4 counts, and CD4 classification categories–for patients at the first time they were assessed by the medical programs. These indicators give information about the stage of disease for the patients when they came into these programs. An additional clinical measure–the physician's severity rating using the Karnofsky index–is also presented. The levels in these four medical indicators are related to a series of indicators of service need and vulnerability status. Several of the service need and vulnerability factors are related to the medical status indicators.

Women enter the programs with higher CD4 counts.


Women enter the programs with higher Karnofsky severity ratings (indicative of good functioning).


Women enter the programs at the higher CDC CD4 categories.

Note: The CD4 categories used here are based on the 1993 guidelines published in MMWR on December 18, 1992 for the three categories of CD4 of 500 or more, 200 - 499, and less than 200. The latter category has been further differentiated by adding a category of CD4 < 50 because of the clinical utility of this category for clinical decisions (see Bartlett's Medical Management of HIV Infection). The CD4 classifications are based on a test made on the same date; unlike the classifications used in some clinical trials and CDC publications, the values given are not nadir (minimum lifetime) values.


At the time of the first assessment of viral loads, women and men had about the same viral loads (within methods of assessment).

More Information:     CHAID and CHAID Diagram

Knowledge Item Citation: Huba, G. J., Melchior, L. A., Panter, A. T., and the HRSA/HAB SPNS Cooperative Agreement Steering Committee (1998-2001). Knowledge Item: CA-Medical Outcomes-01 from HRSA/HAB's SPNS Cooperative Agreements on Innovative Models of Care, The Measurement Group Knowledge Base on HIV/AIDS Care, Online at www.TheMeasurementGroup.com.

Last Updated: March 25, 2005; data through June 15, 1999; analyses conducted February - October 2000.



Knowledge Base Citation: The Knowledge Base and this Knowledge Item were designed and authored by G. J. Huba, Ph.D.; in collaboration with Lisa A. Melchior, Ph.D.; A. T. Panter, Ph.D.; and the staff of The Measurement Group. Cite this work as "Huba, G. J., Melchior, L. A., and Panter, A. T. (1998 - 2001). The Measurement Group Knowledge Base on HIV/AIDS Care. On the World Wide Web: http://www.TheMeasurementGroup.com."

Questions or Comments: Contact The Measurement Group.

Use of Knowledge Base Information: Acceptable Uses and Limitations.

Collaborators from Participating Projects: Cooperative Agreement Steering Committee 1999

Participating Projects: This Knowledge Base is based on the service delivery experiences of 27 Cooperative Agreement Projects on Innovative Models of HIV/AIDS Care. These projects and the Evaluation and Dissemination Center which produced this Knowledge Base were funded by the Health Resources and Services Administration (HRSA), HIV/AIDS Bureau (HAB) as Special Projects of National Significance (SPNS) between 1994 and 1999. Click the Model Programs button above for descriptions of the projects that contributed to this specific Knowledge Item, a list of key staff, and project grant numbers.

Why This Evaluation was Conducted: Editorial.

More Information: Design of this Knowledge Base.

Recommended Citation Format for Web Materials: American Psychological Association Publication Manual Section, Revised 2001.

Work on the Knowledge Base and the cross-cutting evaluation was supported in part by Grant Number 5 U90 HA 00030-05 from the Health Resources and Services Administration (HRSA), HIV/AIDS Bureau's (HAB) Special Projects of National Significance (SPNS). The contents of this Knowledge Base are solely the responsibility of The Measurement Group and do not necessarily represent the official views of HRSA or HRSA/HAB's Special Projects of National Significance nor may they represent the positions of the individual grantees whose projects are included in the cross-cutting evaluation.



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